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. 2012 Jun 19;12:260. doi: 10.1186/1471-2407-12-260

Table 3.

Correlation of tumor subgroups with clinical parameters

Parameter
 
Cluster-1 (n = 35)
Cluster-2 (n = 12)
Cluster-3 (n = 22)
Cluster-4 (n = 14)
p-global
Microsatellite instability
MSS
33
11
21
9
0.039LR,a
 
MSI
2
1
1
5
 
Histologic subtypes
Conventional
34
12
21
8
0.001LR,b
 
Mucinous
1
0
1
6
 
% Stroma content frozen sample
Mean
11.2
18.8
23.4
18.9
<0.001KW,c
 
SD
6.0
10.3
10.5
14.8
 
% Stroma Paraffin
Mean
12.6
17.1
18.9
16.8
0.047KW,d
 
SD
6.0
9.9
8.6
14.2
 
nuclear β-Catenin (IHC)
LOW
21
9
11
12
0.021LR,e
 
MEDIUM
4
0
6
1
 
 
HIGH
10
2
5
0
 
BRAF mutations (V600E)
Mutated
0
1
1
6
<0.001LR,f
 
WT
35
11
21
8
 
Dukes Stage
A
9
5
4
4
0.646LR
 
B
9
3
6
7
 
 
C
8
2
6
2
 
  D 9 2 6 1