Table 3.
Parameter |
|
Cluster-1 (n = 35) |
Cluster-2 (n = 12) |
Cluster-3 (n = 22) |
Cluster-4 (n = 14) |
p-global |
Microsatellite instability |
MSS |
33 |
11 |
21 |
9 |
0.039LR,a |
|
MSI |
2 |
1 |
1 |
5 |
|
Histologic subtypes |
Conventional |
34 |
12 |
21 |
8 |
0.001LR,b |
|
Mucinous |
1 |
0 |
1 |
6 |
|
% Stroma content frozen sample |
Mean |
11.2 |
18.8 |
23.4 |
18.9 |
<0.001KW,c |
|
SD |
6.0 |
10.3 |
10.5 |
14.8 |
|
% Stroma Paraffin |
Mean |
12.6 |
17.1 |
18.9 |
16.8 |
0.047KW,d |
|
SD |
6.0 |
9.9 |
8.6 |
14.2 |
|
nuclear β-Catenin (IHC) |
LOW |
21 |
9 |
11 |
12 |
0.021LR,e |
|
MEDIUM |
4 |
0 |
6 |
1 |
|
|
HIGH |
10 |
2 |
5 |
0 |
|
BRAF mutations (V600E) |
Mutated |
0 |
1 |
1 |
6 |
<0.001LR,f |
|
WT |
35 |
11 |
21 |
8 |
|
Dukes Stage |
A |
9 |
5 |
4 |
4 |
0.646LR |
|
B |
9 |
3 |
6 |
7 |
|
|
C |
8 |
2 |
6 |
2 |
|
D | 9 | 2 | 6 | 1 |