Table 2. Correlation between High and Low Risk HPV status and methylation fraction means at differentially methylated region (DMRs) of PEG3.
Chromosomal region and CpG site | High Risk HPV | Low Risk HPV | Other HPV |
PEG3 (N = 149) | Correlation coefficient (p-value) | Correlation coefficient (p-value) | Correlation coefficient (p-value) |
CpG1 | 0.40 (<0.0001) | −0.01 (0.90) | 0.00 (0.98) |
CpG2 | 0.35 (<0.0001) | 0.02 (0.86) | 0.00 (0.98) |
CpG3 | 0.37 (<0.0001) | 0.03 (0.74) | 0.13 (0.23) |
CpG4 | 0.32 (<0.0001) | −0.01 (0.94) | 0.01 (0.93) |
CpG5 | 0.41 (<0.0001) | −0.04 (0.67) | 0.03 (0.77) |
CpG6 | 0.33 (<0.0001) | −0.04 (0.68) | 0.02 (0.85) |
CpG7 | 0.36 (<0.0001) | −0.01 (0.89) | 0.003 (0.98) |
CpG8 | 0.33 (<0.0001) | 0.001 (0.99) | 0.05 (0.65) |
CpG9 | 0.36 (<0.0001) | −0.04 (0.72) | 0.02 (0.85) |
CpG10 | 0.37 (<0.0001) | −0.01 (0.92) | −0.01 (0.94) |
Mean | 0.34 (<0.0001) | 0.06 (0.55) | 0.02 (0.87) |
High Risk HPV - 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68.
Low/Other Risk HPV – 6, 11, 26,40, 42, 55, 61, 62, 69, 70, 72, 73, 81, 82, 83, 84.