Table 2. Area under the Receiver Operating Characteristic Curve showing the ability of preload variables to predict an increase in stroke volume generated by pulmonary thermodilution ≥15% at baseline and during pleural effusion.

	BL					PLE
	CVP(mmHg)	PAOP(mmHg)	GEDV(ml)	PPV (%)	SVV (%)	CVP(mmHg)	PAOP(mmHg)	GEDV (ml)	PPV (%)	SVV (%)
AUC	0.64	0.65	0.77	0.88	0.85	0.67	0.69	0.92	0.92	0.89
95% CI	0.45–0.84	0.46–0.84	0.61–0.94	0.77–0.99	0.72–0.98	0.51–0.84	0.53–0.85	0.83–1.00	0.84–1.00	0.79–0.99
Threshold value	n.a.	n.a.	>703	<12.5	<11.0	n.a.	>14.5	>584	<15.5	<14.5
Sensitivity (%)	68	63	79	74	74	71	76	95	95	95
Specificity (%)	64	57	64	79	86	57	52	81	71	71
P-value	0.17	0.14	0.007	0.0002	0.0006	0.053	0.034	<0.0001	<0.0001	<0.0001

BL, baseline; PLE, pleural effusion; AUC, area under the curve; 95% CI, 95% confidence interval; CVP, central venous pressure; PAOP, pulmonary artery occlusion pressure; GEDV, global end-diastolic volume; PPV, pulse pressure variation; SVV, stroke volume variation; n.a., not assessed.