Table 2. Haematocrit, haemoglobin concentration, reticulocytes, haemoglobin mass, blood volumes, carboxyhaemoglobin and body mass before, during and 4 weeks post rHuEpo administration.
Baseline | Week 2 of rHuEpo | End of rHuEpo | Week 2 postrHuEpo | Week 4 postrHuEpo | |
Haematocrit (%) | 41.9 (1.8) | 44.7 (2.0)* | 49.2 (2.0)* | 47.7 (2.2)* | 45.1 (1.7)* |
Haemoglobin (g•dl−1) | 14.4 (0.7) | 15.2 (0.7)* | 16.7 (0.9)* | 16.1 (0.9)* | 15.6 (0.7)* |
Reticulocytes (%) | 1.07 (0.31) | 2.57 (0.44)* | 1.46 (0.41)* | 0.44 (0.13)* | 0.55 (0.15)* |
Hbmass (g•kg−1) | 12.7 (1.2) | 13.4 (1.3)* | 15.2 (1.5)* | 15.1 (1.4)* | 13.7 (1.1)* |
Hbmass (g) | 947 (109) | 1001 (127)* | 1131 (131)* | 1126 (136)* | 1023 (132)* |
Blood volume (L) | 6.6 (0.9) | 6.6 (1.0) | 6.8 (0.8) | 6.7 (0.9) | 6.6 (0.8) |
Red cell volume (L) | 2.8 (0.3) | 2.9 (0.3)* | 3.3 (0.4)* | 3.3 (0.4)* | 3.0 (0.4)* |
Plasma volume (L) | 3.8 (0.6) | 3.7 (0.7) | 3.5 (0.4)* | 3.4 (0.6)* | 3.6 (0.5) |
Carboxyhaemoglobin (%) | 0.73 (0.15) | 0.77 (0.16) | 1.04 (0.19)* | 1.01 (0.20)* | 0.65 (0.15) |
Body mass (kg) | 75.1 (8.4) | 74.7 (7.8) | 75.0 (7.9) | 74.6 (7.6) | 74.6 (7.5) |
N = 19. Values are means (SD). Significant differences compared to baseline values are indicated by *P<0.05. Hbmass: Haemoglobin mass.