Figure 2. Other HDIs similarly induced CXCR4 mRNA in human cancer cells. CXCR4 mRNA was measured by qPCR in H460, SF295, MCF7, UOK121 cells treated with apicidin (1-2-5 μM), vorinostat (2.5-5-7.5 μM), MS-275 (2-4-10 μM) or romidepsin (1-2-5 ng/ml + verapamil 5 μg/mL) for 24 h. rRNA was used as the internal control. Results from three independent experiments are shown.