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The system is composed of a homotetrameric Kv1.2 channel with paddle chimera (PDB-ID: 2r9r; shown as cyan ribbons), a POPE membrane (shown as gray sticks), and a KCl solution (waters, potassium ions, and chloride ions are depicted as red dots, green balls, and cyan balls, respectively). The electric field was applied toward the extracellular side (shown as the arrow labeled ‘E’).
