Table 1. Baseline characteristics stratified by serum Mg levels in T2D subjects.
| T2D (n = 137) | CON (n = 50) | |||
| Low-Mg (n = 48) | High-Mg (n = 89) | P | High-Mg (n = 50) | |
| Age (years) | 52 (44–60) | 58 (47–65) | 0.038* | 55 (45–63) |
| Sex, male (%) | 37 (77.1) | 48 (53.9) | 0.008* | 31 (62.0) |
| BMI (kg/m2) | 25.6 (23.0–27.7) | 25.2 (23.3–27.5) | 0.799 | 21.6 (19.5–22.9) |
| Glu (mmol/L) | 8.5 (7.3–11.7) | 8.8 (7.7–11.2) | 0.434 | 4.8 (4.1–5.6) |
| HbA1c (%) | 8.3 (7.0–8.9) | 8.3 (7.3–9.1) | 0.472 | 5.1 (4.2–6.0) |
| RBC (×1012) | 4.9 (4.6–5.1) | 4.7 (4.2–5.0) | 0.026* | 4.8 (4.3–5.0) |
| Hb (g/L) | 146.0 (136.3–156.3) | 139.0 (127.0–153.0) | 0.235 | 133.2 (128.1–153.7) |
| BUN (mmol/L) | 6.5 (5.1–12.1) | 5.9 (5.2–7.9) | 0.031* | 5.5 (4.2–6.4) |
| Cre (µmol/L) | 81.1 (65.5–238.8) | 76.9 (63.6–112.8) | 0.005* | 73.9 (63.1–80.9) |
| eGFR (ml/min) | 94.0 (37.9–117.6) | 85.7 (57.6–110.9) | 0.656 | 24.6 (22.7–26.4) |
| Hypertension (%) | 18 (37.5) | 40 (44.9) | 0.402 | 0 |
| Dyslipidemia (%) | 30 (62.5) | 47 (52.8) | 0.277 | 0 |
| Ca (mg/L) | 63.0 (53.6–72.6) | 107.6 (92.5–138.9) | 0.000* | 165.0 (145.8–177.2) |
| UCa (mg/L) | 94.2 (43.4–151.6) | 79.2 (38.2–136.6) | 0.391 | 63.3 (31.0–94.1) |
| UMg (mg/L) | 54.8 (40.6–79.6) | 47.7 (39.4–73.5) | 0.048* | 34.4 (15.1–47.3) |
| CHO (mmol/L) | 5.0 (4.4–5.9) | 5.0 (4.4–6.3) | 0.234 | 4.5 (3.2–5.1) |
| TG (mmol/L) | 1.6 (1.0–2.8) | 1.5 (1.1–2.7) | 0.578 | 1.2 (1.0–1.4) |
| HDL (mmol/L) | 1.1 (0.9–1.5) | 1.2 (1.1–1.5) | 0.514 | 1.2(1.1–1.3) |
| LDL (mmol/L) | 3.2 (2.6–3.8) | 3.4 (2.7–3.9) | 0.426 | 2.4 (2.0–2.9) |
Data are presented as number (%) or median (interquartile range). Baseline characteristics were adjusted for age, sex, BMI, hypertension and dyslipidemia by analysis of covariance using general linear models.
*
, P<0.05 vs High-Mg group. BMI: body mass index, Glu: serum glucose, HbA1c: glycated hemoglobin, RBC: red blood cell, Hb: hemoglobin, BUN: blood urea nitrogen, Cre: serum creatinine, eGFR: estimating GFR, Ca: serum calcium, UCa: urinary calcium, Mg: serum magnesium, Umg: urinary magnesium, CHO: total cholesterol, TG: triglyceride, HDL: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol.