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. 2013 Feb 13;8(2):e56333. doi: 10.1371/journal.pone.0056333

Figure 3. Kaplan-Meier survival curves for histological NSCLC subtypes.

Figure 3

NSCLC subtypes were diagnosed by H&E on resection specimens (A) and by combined IHC classification algorithm (B). Additional IHC classification separates distinct histological entities suggesting different biological behavior. Grouping the different entities according to therapeutic consequences (C and D), no differences in survival are evident by conventional H&E classification of resection specimens (C), whereas combined IHC classification significantly separates the different survival curves (p = 0.045; D).