Table 3. Cross-tabulation for concordance or H&E-classification and IHC-classification with classification of resection specimens.
H&E resection specimen | |||||
TMA-IHC | LAC | SCC | LCC | LCNEC | Total |
LAC | 80 | 5 | 4 | 1 | 90 |
SCC | 7 | 91 | 26 | 3 | 127 |
LCNEC | 7 | 4 | 0 | 19 | 30 |
Mixed LAC/SCC | 3 | 1 | 1 | 0 | 5 |
NSCLC | 3 | 1 | 8 | 1 | 13 |
Total | 100 | 102 | 39 | 24 | 265 |
Cramer's V 0.629, p<0.001 |
Combining all TMA cores to a single diagnosis IHC-classification shows higher concordance with the diagnosis made upon the resection specimen as consensus H&E diagnosis of the TMA cores.