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. 2013 Feb 13;8(2):e56741. doi: 10.1371/journal.pone.0056741

Table 2. Samples with A20 deletions and/or the absence of A20 by immunohistochemistry.

Sample No. Diagnosis A20 deletion A20 expression EBER1 (ISH) LMP-1 EBNA-2
1 PAL Homozygous loss + + +
2 PAL LOH + + +
3 PAL LOH +/− + + +
4 PAL LOH +/− + + +
5 NKTL Homozygous loss u.d. +
6 NKTL LOH u.d. +
7 NKTL LOH +/− +
8 DLBCL-e LOH + + +
9 MTX-LPD normal + +

Abbreviations: PAL, pyothorax-associated lymphoma; NKTL, NK/T cell lymphoma, nasal type; DLBCL-e, EBV positive diffuse large B-cell lymphoma of the elderly; MTX-LPD, methotrexate-related lymphoproliferative disorders; LOH, loss of heterozygosity; EBER1, Epstein-Barr virus encoded RNA1; LMP-1, latent membrane protein-1; EBNA-2, EBV nuclear antigen-2; +, positive (50% or more); p+, intermediate expression (less than 50%); −, negative (0%); +/−, equivocal positive; u.d., undetermined.