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. 2013 Feb 13;8(2):e52779. doi: 10.1371/journal.pone.0052779

Figure 4. Lipid profiles according to genotypes.

Figure 4

Patients with QQ/QR genotypes had lower triglyceride levels (Fig. 4A). As for LDL particle size, there was no difference either in VLDL, IDL between both groups (Fig. 4B), or large and medium sized LDL (Fig. 4C). As for small LDL, patients with QQ/QR genotype had significant higher LDL-IIIA than those RR-genotype (1.20±0.12 mg/dL vs. 0.76±0.15 mg/dL, P = 0.027) (Fig. 4D). Cholesterol level was compared by using one-way ANOVA test. As for LDL-particle size, general linear model analysis was applied to quantify the effect of PON-1 QQ/QR genotype on LDL-particle size after adjustment for age, sex, triglyceride level, HDL-C level, and statin use. Data were presented as the mean ± the SEM.