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. 2013 Feb 13;8(2):e52779. doi: 10.1371/journal.pone.0052779

Table 2. Clinical outcome according to PON1-Q192R genotype.

QQ/QR, n = 815 RR, n = 521 p-value
Primary composite end point of cardiac death, MI, and ST 18 (2.2%) 1 (0.2%) 0.002
Secondary end points
Cardiac Death 8 (1.0%) 1 (0.2%) 0.085
Myocardial infarction 11 (1.3%) 0 (0.0%) 0.008
CVA 1 (0.1%) 0 (0%) 0.422
Stent thrombosis 8 (1.0%) 0 (0.0%) 0.023
Target lesion revascularization 80 (9.8%) 47 (9.0%) 0.590
Composite of Death, MI, CVA 16 (2.3%) 4 (0.6%) 0.002
MACE 113 (13.9%) 54 (10.4%) 0.052

MI, myocardial infarction; ST, stent thrombosis; CVA; cerebrovascular accident; MACCE, major adverse cardiovascular event.

P-value by Log-rank test.