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. 2013 Feb 13;8(2):e55313. doi: 10.1371/journal.pone.0055313

Table 1. Tumor growth after treatment with single factor (Ad5/F35-siAPE1 or irradiation) or combination on hepatoma tumor model.

HepG2 xenografts MHCC97L xenografts
Experimental groups N DT (days) Mean±SD SGD Mean±SD Inhibitionratio (%) N DT (days) Mean±SD SGD Mean±SD Inhibitionratio (%)
Ad5/F35-EGFP 4 3.48±0.13 4 3.56±0.17
Ad5/F35-siAPE1 4 3.9±0.1 0.12±0.07 30.5 4 4.09±0.06 0.15±0.07 29.56
Ad5/F35-EGFP+IR 4 3.86±0.14 0.11±0.07 28 4 3.9±0.11 0.1±0.07 25.76
Ad5/F35-siAPE1+IR 4 6.1±0.47 0.75±0.08 74.65 4 5.73±0.16 0.61±0.07 72.15

IR = irradiation; N = number of mice in the experimental group; DT = tumor doubling time; SGD = specific growth delay.