Table 1. Tumor growth after treatment with single factor (Ad5/F35-siAPE1 or irradiation) or combination on hepatoma tumor model.
HepG2 xenografts | MHCC97L xenografts | ||||||||
Experimental groups | N | DT (days) Mean±SD | SGD Mean±SD | Inhibitionratio (%) | N | DT (days) Mean±SD | SGD Mean±SD | Inhibitionratio (%) | |
Ad5/F35-EGFP | 4 | 3.48±0.13 | 4 | 3.56±0.17 | |||||
Ad5/F35-siAPE1 | 4 | 3.9±0.1 | 0.12±0.07 | 30.5 | 4 | 4.09±0.06 | 0.15±0.07 | 29.56 | |
Ad5/F35-EGFP+IR | 4 | 3.86±0.14 | 0.11±0.07 | 28 | 4 | 3.9±0.11 | 0.1±0.07 | 25.76 | |
Ad5/F35-siAPE1+IR | 4 | 6.1±0.47 | 0.75±0.08 | 74.65 | 4 | 5.73±0.16 | 0.61±0.07 | 72.15 |
IR = irradiation; N = number of mice in the experimental group; DT = tumor doubling time; SGD = specific growth delay.