Figure 1. Vitamin D metabolism.
1,25(OH)2D and PTH influence vitamin D metabolism by positive (+) or negative (−) regulation of the activity of the 1α-hydroxylase and the 24-hydroxylase. 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)2D, 1,25-dihydroxyvitamin D; 24,25(OH)2D, 24,25-dihydroxyvitamin D; 1,24,25(OH)3D, 1,24,25-trihydroxyvitamin D.