Table 5. Selected SNPs analysed in 52 individuals with primary hyperparathyroidism.
| rs number | Genotype major/minor homozygote | Frequency major/minor homozygote | Included samples | HWE p-value | |||
| VDR | |||||||
| rs1544410 (Bsm1) | GG/AA | 0.37/0.13 | 52 | 0.44 | |||
| rs7975232 (Apa1) | CC/AA | 0.21/0.18 | 51 | 0.12 | |||
| rs2228570 (Fok1) | CC/TT | 0.35/0.13 | 52 | 0.27 | |||
| 25-hydroxylase (Cyp2R1) | |||||||
| rs10741657 | GG/AA | 0.44/0.21 | 52 | 0.14 | |||
| 24-hydroxylase (Cyp24a1) | |||||||
| rs6013897 | TT/AA | 0.36/0.08 | 52 | 0.19 | |||
| rs2762939 | GG/CC | 0.46/0.06 | 52 | 0.21 | |||
| 1-alfa hydroxylase (Cyp27B1) | |||||||
| Rs10877012 | GG/TT | 0.53/0.12 | 51 | 0.25 | |||
Only samples without missing values were included in the analyses. P-values for Hardy Weinberg equilibrium are based on a chi-squared test. SNP, single nucleotide polymorphism; HWE, Hardy Weinberg equilibrium; VDR, vitamin D receptor.