. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: Drug Alcohol Depend. 2012 Oct 18;129(1-2):102–109. doi: 10.1016/j.drugalcdep.2012.09.015

Table 3.

Phosphorus metabolite levels in the frontal lobe

	Methamphetamine			Healthy			p-value
	Total			Total
Metabolites^†	(n=51)	Female	Male	(n=23)	Female	Male
PCr	.212 (.021)^*	.205 (.019)^**	.217 (.021)^**	.230 (.016)^*	.225 (.018)	.231 (.014)	.001^*
β-NTP	.192 (.022)	.195 (.025)	.189 (.019)	.189 (.020)	.187 (.027)	.190 (.013)	.58
PME	.215 (.037)	.220 (.041)	.210 (.033)	.218 (.022)	.215 (.027)	.221 (.018)	.68
PDE	.286 (.036)	.291 (.036)	.281 (.037)	.292 (.034)	.285 (.034)	.298 (.034)	.47
Pi	.076 (.012)	.080 (.012)	.074 (.013)	.074 (.012)	.073 (.013)	.075 (.012)	.38

Data are expressed with mean (SD);

^†

metabolite ratios over total pool of exchangeable phosphate;

Indicates statistically significant PCr differences between methamphetamine and healthy group (p=.001);

^**

Indicates significant PCr differences between female and male methamphetamine users (p=.04). For other metabolites, there were neither group differences nor within-group gender differences.

Abbreviations: PCr, phosphocreatine; β-NTP, beta-nucleoside triphosphate; PME, phosphomonoester; PDE, phosphodiester; Pi, inorganic phosphate.