Table 2.
Univariate analysis of potential risk factors for immediate post-resection diabetes mellitus (iPRDM) in patients undergoing a pancreaticoduodenectomy
| Variable | Odds ratio (95% CI) | P-value |
|---|---|---|
| Year of operation (1-year increase) | 0.79 (0.62–1.00) | 0.046 |
| Age at operation (10-year increase) | 1.27 (0.88–1.83) | 0.21 |
| Male | 3.88 (1.30–11.62) | 0.015 |
| Pre-operative FBG (20-unit increase) | 1.91 (1.47–2.47) | <0.001 |
| Preoperative FBG | ||
| <100 mg/dl | 1.0 (reference) | |
| 100–125 mg/dl | 3.65 (0.78–17.10) | 0.1 |
| ≥126 mg/dl | 20.11 (4.26–94.87) | <0.001 |
| Impaired glucose tolerance | 26.11 (9.59–71.15) | <0.001 |
| Family history of DM | 0.87 (0.33–2.32) | 0.78 |
| Hypertension | 1.61 (0.68–3.79) | 0.28 |
| BMI (5-unit increase) | 2.00 (1.34–2.99) | <0.001 |
| BMI ≥30 | 2.38 (0.97–5.82) | 0.06 |
| Pre-operative creatinine (1-unit increase) | 3.83 (1.25–11.76) | 0.019 |
| Pre-operative creatinine > 1.2 | 2.67 (0.86–8.32) | 0.09 |
| Laparoscopic approach | 0.61 (0.14–2.68) | 0.52 |
| Pylorus preserving | 0.81 (0.29–2.24) | 0.68 |
| Operative time (100-minute increase) | 1.80 (1.13–2.85) | 0.013 |
| Estimated blood loss (500-cc increase) | 1.21 (0.95–1.54) | 0.12 |
| Transfusion | 1.29 (0.55–3.03) | 0.56 |
| Malignant disease | 0.72 (0.29–1.80) | 0.48 |
| Tumour size (1-cm increase) | 1.16 (1.03–1.32) | 0.019 |
| Specimen length (1-cm increase) | 1.40 (1.11–1.78) | 0.005 |
FBG, fasting blood glucose; DM, diabetes mellitus; BMI, body mass index (kg/m2).