Table 3.
Percent differencea in hormone level (95% confidence intervals,) relative to population median, associated with an interquartile range (IQR) increase in house dust BFR concentration
| PentaBDEc (n=62)f | OctaBDEd (n=38) | DecaBDEe (n=38) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| p-value | p-value | p-value | |||||||
| FSH | −20.2 | (−34.7, −2.5) | 0.03 | 4.4 | (−13.2, 25.6) | 0.65 | 1.8 | (−15.5, 22.7) | 0.85 |
| LH | −9.4 | (−24.1, 8.2) | 0.28 | 15.5 | (0.6, 32.6) | 0.05 | −6.6 | (−19.2, 8.1) | 0.37 |
| Inhibin B | 18.2 | (−4.8, 41.3) | 0.13 | −5.8 | (−29.4, 17.7) | 0.63 | −6.2 | (−29.9, 17.5) | 0.61 |
| Testosteroneb | 3.6 | (−7.4, 14.7) | 0.52 | 9.0 | (0.8, 17.2) | 0.03 | −9.4 | (−17.6, −1.2) | 0.02 |
| SHBG | 16.8 | (0.7, 35.4) | 0.05 | 9.2 | (−6.1, 27.0) | 0.26 | −10.2 | (−22.8, 4.4) | 0.17 |
| FAI | −10.6 | (−22.5, 3.2) | 0.13 | −0.7 | (−13.9, 14.5) | 0.92 | 0.4 | (−13.0, 16.0) | 0.95 |
| Estradiol | 17.1 | (0.0, 34.2) | 0.05 | 14.4 | (−2.8, 31.7) | 0.11 | −8.5 | (−26.3, 9.3) | 0.36 |
| Prolactin | 10.8 | (−6.0, 30.7) | 0.23 | 13.8 | (−2.9, 33.4) | 0.12 | 4.5 | (−11.4, 23.3) | 0.60 |
| Free T4 | 3.6 | (0.6, 6.5) | 0.02 | 3.3 | (1.0, 5.6) | 0.01 | −1.7 | (−4.2, 0.9) | 0.20 |
| Total T3 | 5.4 | (0.0, 10.7) | 0.05 | 4.3 | (−0.2, 8.8) | 0.07 | 1.7 | (−3.1, 6.4) | 0.50 |
| TSH | 14.1 | (−4.7, 36.7) | 0.16 | 21.2 | (0.8, 45.8) | 0.05 | 11.1 | (−8.5, 34.9) | 0.29 |
Adjusted for age and BMI.
Free testosterone estimated using equation by Vermeulen et al. 1999.
PentaBDE is sum of BDE 47, 99 and 100. IQR = 2268 ng/g for n=38 and 2985 ng/g for n=60.
OctaBDE is sum of BDE 183 and 201. IQR = 39 ng/g.
DecaBDE is sum of BDE 206, 207, 208 and 209. IQR = 1876 ng/g.
Includes additional 24 samples from prior preliminary analysis, and models are also adjusted for difference in dust analytical method.