Table 2.
Subjective measures on which there was a significant difference between the two drugs
| Subjective effect | KET | TRZ | Low dose | High dose |
|---|---|---|---|---|
| Drug effect | >PL | >PL | KET>TRZ | KET>TRZ |
| Confused/disoriented | >PL | >PL | KET>TRZ | KET>TRZ |
| Forgetful | >PL | >PL | NS | KET>TRZ |
| Mentally slowed down | >PL | >PL | NS | KET>TRZ |
| Bad effects | >PL | >PL | KET>TRZ | KET>TRZ |
| Dislike drug | >PL | >PL | KET>TRZ | KET>TRZ |
| Light headed/dizzy | >PL | >PL | KET>TRZ | KET>TRZ |
| Unsteady | >PL | >PL | KET>TRZ | KET>TRZ |
| Limbs heavy/rigid | >PL | >PL | NS | KET>TRZ |
| Queasya | >PL | >PL | NS | KET>TRZ |
| Nervous/anxious | >PL | KET>TRZ | KET>TRZ | |
| Numbness/tingling | >PL | KET>TRZ | KET>TRZ | |
| Headache | >PL | NS | KET>TRZ | |
| Dry mouth | >PL | NS | KET>TRZ | |
| Hot/flushed | >PL | NS | KET>TRZ | |
| Shaky or jittery | >PL | NS | KET>TRZ | |
| Speech slurred | >PL | NS | KET>TRZ | |
| Arousing/stimulantb | >PL | NS | KET>TRZ | |
| Sleepy | >PL | >PL | NS | TRZ>KET |
| Comfortable | <PL | NS | TRZ>KET | |
| Relaxed | <PL | NS | TRZ>KET |
TRZtriazolam, KET ketamine, PL placebo, NS not significant
a
Significant effect of task order on this measure. Significant difference when questionnaire occurs late in the assessment battery
b
Significant effect of task order on this measure. Significant difference when questionnaire occurs early in the assessment battery