Fig. 5.

Comparison of patients less than or greater than 55 years of age in terms of their responses to ibuprofen or ibuprofen-phosphatidylcholine (PC). Younger subjects had fewer ibuprofen-associated gastroduodenal lesions than those >55 years. Those over 55 years taking ibuprofen were 3.7 times more likely to develop multiple gastroduodenal erosions than those taking an equivalent nonsteroidal anti-inflammatory drug (NSAID) dose of ibuprofen-PC. In brief, Lanza scores are broken down into the following values: 0, normal mucosa; 1, mucosal hemorrhages only; 2, one or two erosions; 3, three to ten erosions; 4, greater than 10 erosions or an ulcer (defined as a mucosal break with a diameter of 3 mm or more, with depth).

^*p<0.02 vs ibuprofen.