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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Metabolism. 2012 Nov 9;62(4):539–547. doi: 10.1016/j.metabol.2012.10.001

Table 2.

Correlations between calcium-regulatory hormones and adipocytokines and inflammatory markers in the Protocol 1 study population.

Study Visit 1 (Pre-Vitamin D3 Intervention) Study Visit 2 (Post-Vitamin D3 Intervention)
25(OH)D 1,25(OH)2D PTH 25(OH)D 1,25(OH)2D PTH
Fasting glucose (mg/dL) −0.49† −0.54* 0.40 0.10 −0.58* 0.16
Fasting insulin (μIU/mL) −0.08 0.03 −0.27 0.14 −0.37 −0.00
HOMA-IR −0.16 −0.05 −0.20 0.15 −0.42 0.02
IL-6 (pg/mL) 0.33 0.37 −0.48 −0.04 −0.45 −0.29
PAI-1 (ng/mL) −0.31 −0.33 0.66* −0.29 0.38 0.59*
Urinary TGF-β1/urine Creatinine (μg/dL) −0.09 0.42 0.62* −0.39 −0.30 0.31
Adiponectin (μg/mL) −0.31 −0.53* 0.34 −0.05 −0.68* 0.15
Resistin (μg/L) 0.22 0.52† 0.16 0.23 0.40 0.33
Leptin (ng/mL) 0.02 −0.17 0.41 0.19 −0.05 0.31

Table displays Pearson correlation coefficients (r) before and after vitamin D3 therapy (

†

P<0.10,

*

P<0.05).

25(OH)D=25-hydroxyvitamin D; 1,25(OH)2D = 1,25-dihydroxyvitamin D; PTH=parathyroid hormone; HOMA-IR=homeostatic model for insulin resistance; IL-6=interleukin 6; PAI-1=plasminogen activator inhibitor 1.