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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Stem Cells. 2013 Feb;31(2):397–407. doi: 10.1002/stem.1270

Figure 4.

Figure 4

MSCs protect organs from injury after CLP-induced polymicrobial sepsis. HO-1−/− mice underwent sham (−) or CLP (+) surgery, and 2 hours after surgery were treated with MSCs or fibroblasts. At 24 hours after surgery, tissues were scored for injury (see Methods section). Horizontal bars represent mean values. Sham, n=8–10; MSCs, n=9–10; fibroblasts, n=9–10 for the kidney, liver and spleen. Sham, n=6; MSCs, n=7; fibroblasts, n=4 for the small bowel. *P<0.05 versus sham, †P<0.05 versus fibroblasts using Kruskal-Wallis one-way analysis of variance followed by the Dunn’s post test analysis.