Table 2.
Lifespan analyses frh-1 RNAi on different kinase mutants — summary statistics.
| Genotype | RNAi | Mean Lifespan | + SEM | p vs con⁎ | p vs N2⁎ | Sample size (censored)a | N of replicates |
|---|---|---|---|---|---|---|---|
| Wild-type (N2) | con | 17.2 | 0.2 | 460 (40) | 7 | ||
| frh-1 | 20.6 | 0.3 | 4.9E − 17 | 468(100) | 7 | ||
| aak-2(rr48) | con | 12.6 | 0.3 | 1.06E − 26 | 198 (61) | 3 | |
| frh-1 | 16.3 | 0.4 | 1.5E − 12 | 0.17044 | 197 (43) | 3 | |
| aak-2(ok524) | con | 17.9 | 0.3 | 0.20326 | 319 (53) | 5 | |
| frh-1 | 23.1 | 0.3 | 1.5E − 27 | 1.39E − 34 | 330 (54) | 5 | |
| aak-1(tm1994) | con | 16.5 | 0.4 | 0.33077 | 190 (28) | 3 | |
| frh-1 | 21.5 | 0.6 | 3.6E − 08 | 1.06E − 10 | 191 (61) | 3 | |
| aak-1(tm1994); aak-2(ok524) | con | 14.6 | 0.3 | 3.85E − 01 | 191 (57) | 3 | |
| frh-1 | 17.9 | 0.3 | 6.9E − 10 | 0.38536 | 188 (38) | 3 | |
| par-4(it57) | con | 16.6 | 0.5 | 0.40960 | 140 (40) | 2 | |
| frh-1 | 21.2 | 0.5 | 1.6E − 08 | 2.44E − 10 | 140 (35) | 2 | |
| Wild-type (N2) | con | 16.4 | 0.3 | 200(10) | 3 | ||
| frh-1 | 19.8 | 0.4 | 1.2E − 08 | 1.17E − 08 | 200(32) | 3 | |
| sad-1(ky289) | con | 15.8 | 0.6 | 0.78698 | 120(46) | 2 | |
| frh-1 | 20.8 | 1.0 | 0.00003 | 0.00001 | 121(40) | 2 | |
| kin-29(gk270) | con | 12.1 | 0.2 | 1.29E − 18 | 139(22) | 2 | |
| frh-1 | 16.1 | 0.4 | 5.1E − 12 | 0.72663 | 141(30) | 2 | |
| mml-1(ok849) | con | 15.2 | 0.4 | 0.23012 | 200(40) | 3 | |
| frh-1 | 19.6 | 0.4 | 1.5E − 09 | 7.96E − 08 | 199(30) | 3 | |
⁎
p-values were calculated using the log-rank test between pooled populations.
a
Pooled worms from N replicate experiments (censored individuals were included in the log rank analysis).