Table 1.
Effects of the methanol extract from C. zeylanicum on lipid profile in L-NAME hypertensive rats
| Treatment | Triglycerides (mg/dl) | Total cholesterol (mg/dl) | HDL-cholesterol (mg/dl) | LDL-cholesterol (mg/dl) | Atherogenic index |
|---|---|---|---|---|---|
| Control |
53.48 ± 3.36 |
50.63 ± 2.07 |
48.76 ± 3.13 |
5.51 ± 3.68 |
1.06 ± 0.31 |
| L-NAME |
81.10 ± 3.80β |
83.13 ± 4.02γ |
17.57 ± 2.82β |
38.52 ± 4.29β |
5.35 ± 0.48γ |
| L-N + Capto |
45.74 ± 3.36** |
48.12 ± 2.09*** |
40.40 ± 3.32** |
4.50 ± 3.96*** |
1.50 ± 0.70*** |
| L-N + MECZ | 50.16 ± 3.33* | 56.46 ± 5.29*** | 42.26 ± 3.83** | 9.50 ± 3.08*** | 1.41 ± 0.18*** |
n = 5; βp < 0.01 and γp < 0.001 significantly different compared to the control; *p < 0.05, **p < 0.01 and ***p < 0.001 significantly different compared to L-NAME. L-NAME group received only L-NAME 40 mg/kg/day. L-N + Capto received L-NAME plus captopril (20 mg/kg/day) while L-N + MECZ received L-NAME plus extract (300 mg/kg/day).