Table 1.
Variable |
Women with BC n (mean) |
Women without BC n (mean) |
Crude OR1 |
Adjusted OR2 |
Pvalue |
---|---|---|---|---|---|
(95% CI) | (95% CI) | ||||
Age (continuous)* |
285 (56.7) |
539 (52.4) |
1.02 (1.02,1.04) |
1.02 (1.01, 1.05) |
0.001 |
Number of children |
273(2.4) |
517 (2.1) |
1.2 (1.1, 1.3) |
1.1 (1.0, 1.3) |
0.055 |
# Missing (34) | |||||
Increasing BMI (continuous)* |
284 (27.8) |
534 (27.2) |
1.02 (0.9, 1.1) |
1.03 (1.0, 1.1) |
0.118 |
# Missing (6) | |||||
Family history of BC | |||||
Yes |
64 |
78 |
1.7 (1.2, 2.5) |
1.7 (1.0, 2.8) |
0.054 |
No |
221 |
461 |
|
|
|
Marital status | |||||
Married |
154 |
362 |
Referent |
Referent |
|
Single |
61 |
92 |
4.2 (2.2, 7.8) |
5.9 (2.3, 15.6) |
<0.001 |
Divorced |
40 |
66 |
2.7 (1.4, 5.3) |
3.6 (1.2, 10.5) |
0.025 |
Widow |
30 |
17 |
2.9 (1.4, 5.9) |
4.6 (1.6, 13.7) |
0.006 |
# Missing (2) | |||||
Irregular menstrual cycles | |||||
Yes |
183 |
320 |
1.2 (0.9,1.6) |
1.4 (0.8, 2.2) |
0.207 |
No |
102 |
213 |
|
|
|
# Missing (6) | |||||
History of pregnancy | |||||
Yes |
220 |
401 |
1.2 (0.8,1.6) |
1.4 (0.8,2.2) |
0.382 |
No |
65 |
138 |
|
|
|
History of breastfeeding | |||||
Yes |
122 |
246 |
0.8 (0.6, 1.1) |
0.8 (0.5, 1.2) |
0.256 |
No |
118 |
194 |
|
|
|
# Missing (144) | |||||
Alcohol intake | |||||
Yes |
42 |
98 |
0.8 (0.6, 1.2) |
0.8 (0.5, 1.7) |
0.526 |
No |
243 |
441 |
|
|
|
Smoking | |||||
Yes |
37 |
48 |
1.6 (0.9, 2.4) |
1.1 (0.6, 2.1) |
0.707 |
No | 248 | 491 |
*Mean values presented in parenthesis.
Comparisons were measured with the crude1 and the adjusted2 multiple logistic regression odds ratio (OR)3 in the total sample divided by patients and women without breast cancer.
1Crude or unadjusted analysis: The analysis is carried out without taking into consideration potential confounders.
2Adjusted analysis: The analysis is carried out adjusting for the potential effect of all confounding variables simultaneously by using logistic regression model. The associations were adjusted by DRC, age, body mass index, family history of breast cancer, number of children, marital status, and/or smoking.