Table 3.
Number of similar toxicological endpoints
| Chemical name | CAS number | # similar general developmental toxicity endpoints | # similar morphological developmental toxicity endpoints | p-value |
|---|---|---|---|---|
|
Metam-sodium |
137-42-8 |
3 |
3 |
5.6e-03 |
|
Mepiquat chloride |
24307-26-4 |
0 |
2 |
9.3e-03 |
|
Clomazone |
81777-89-1 |
2 |
3 |
9.3e-03 |
|
6-Deisopropylatrazine |
1007-28-9 |
0 |
2 |
9.3e-03 |
| Zoxamide |
156052-68-5 |
0 |
0 |
9.3e-03 |
|
Iprodione |
36734-19-7 |
4 |
2 |
9.3e-03 |
| Monosodium methane arsenate |
2163-80-6 |
3 |
0 |
9.3e-03 |
|
Cyprodinil |
121552-61-2 |
2 |
2 |
9.5e-03 |
|
Carfentrazone-ethyl |
128639-02-1 |
0 |
1 |
1.3e-02 |
|
Primisulfuron-methyl |
86209-51-0 |
1 |
3 |
1.3e-02 |
| 3-(3,5-Dichlorophenyl)-1,5-dimethyl-3-azabicyclo(3.1.0)hexane-2,4-dione |
32809-16-8 |
0 |
0 |
1.7e-02 |
| Bromadiolone |
28772-56-7 |
1 |
0 |
1.7e-02 |
| MGK 264 |
113-48-4 |
0 |
0 |
2.5e-02 |
|
Diniconazole |
83657-24-3 |
3 |
3 |
2.5e-02 |
|
Difenoconazole |
119446-68-3 |
3 |
1 |
2.5e-02 |
| Fenpropathrin |
39515-41-8 |
1 |
0 |
2.5e-02 |
|
Fenbuconazole |
114369-43-6 |
4 |
1 |
2.5e-02 |
| Bendiocarb |
22781-23-3 |
2 |
0 |
2.5e-02 |
| Dacthal |
1861-32-1 |
1 |
0 |
2.5e-02 |
|
Fludioxonil |
131341-86-1 |
0 |
2 |
2.5e-02 |
|
Mancozeb |
8018-01-7 |
3 |
3 |
2.5e-02 |
|
Triadimenol |
55219-65-3 |
0 |
3 |
2.5e-02 |
|
Myclobutanil |
88671-89-0 |
2 |
1 |
2.5e-02 |
|
Cyproconazole |
94361-06-5 |
2 |
2 |
2.9e-02 |
| Fluroxypyr |
69377-81-7 |
1 |
0 |
3.1e-02 |
|
Fluazifop-P-butyl |
79241-46-6 |
2 |
4 |
3.5e-02 |
|
Ethametsulfuron methyl |
97780-06-8 |
4 |
2 |
3.5e-02 |
| Cyclanilide |
113136-77-9 |
0 |
0 |
3.8e-02 |
|
EPTC |
759-94-4 |
4 |
1 |
4.1e-02 |
| Metaldehyde |
108-62-3 |
1 |
0 |
4.1e-02 |
| Cyhexatin |
13121-70-5 |
3 |
0 |
4.1e-02 |
|
Pyrimethanil |
53112-28-0 |
3 |
2 |
4.1e-02 |
| Nitrapyrin | 1929-82-4 | 1 | 1 | 4.7e-02 |
Number of similar toxicological endpoints and false discovery rate-corrected p-values for chemicals predicted similar to the triazole gene expression data set using the weighted global test. Chemicals with a similar morphological developmental in vivo toxicity profile to triazoles are in bold.