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Mice were injected i.c.v. with T1AM (0.4, 1.32 and 4 μg·kg−1) or vehicle and put on the hole-board platform. Movements and exploratory activities were monitored as described in the Methods section. Results are expressed as mean ± SEM; n = 20 in each group; ***P < 0.001 and **P < 0.01 versus vehicle.
