Figure 6.

Effect of chronic administration of saline or PK2 on food intake and body weight in diet-induced obese mice. Cumulative food intake (A) and body weight change (B) in diet-induced obese mice implanted with a mini-osmotic pump containing either saline, PK2 (60 nmol kg⁻¹ h⁻¹) or PK2 (120 nmol kg⁻¹ h⁻¹). Figure 4: *P < 0.05, **P < 0.01 60 nmol kg⁻¹ h⁻¹ PK2 versus saline; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 120 nmol kg⁻¹ h⁻¹ PK2 versus saline, n = 10–11 per group. Figure 4: ***P < 0.001 all groups versus saline.