Figure 3.

PMX205 attenuates DSS-induced histopathological features in BALB/c mice. (A) Representative figures of the colon prepared from (a,d) untreated, (b,e) control and (c,f) PMX205 groups. In (b,c) ovals identify the ulcers along the length of the colon. Compared with the control group, PMX205-treated mice typically showed fewer and shorter ulcers, less crypt damage, fewer mice with oedema and less of the colon was infiltrated. (B) The inflammation score was determined from these criteria by an investigator blinded to the treatment. Each dot is the data from a single mouse and the line represents the median of the inflammation scores. **P < 0.01 versus controls.