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. Author manuscript; available in PMC: 2013 Feb 14.
Published in final edited form as: ACS Nano. 2012 Nov 2;6(11):10366–10377. doi: 10.1021/nn304347g

Figure 5.

Figure 5

Biodistribution and validation. (A) Time course biodistribution data indicates a blood pool supply greater than 10% ID/g for at least 6 hours after intravenous injection. Major sites of accumulation include the spleen and the liver, typical of RES uptake. Tumor accumulation peaks at 3 h at 3.8±1.0%ID/g. (B) Importantly, there is a positive linear relationship between the concentration of gold in the tumor and PA signal. Both the PA signal and gold concentration peak at 3 h postinjection. In panel A error bars represent the standard deviation of three animals; error bars in panel B are the standard error.