Table 5.

Coefficients of variation reported for tPSA and fPSA.

Study	Time Span, weeks	Prostate Conditions	No. Participants	Measure	tPSA	fPSA
Riehmann, 1993 [23]	30	BPH	129	CVt	≤58%	na
Prestigiacomo, 1996 [29]	3	PCa, BPH	169	CVb	23.5%	na
Nixon, 1997 [16]	2	PCa, BPH	9	CVt	7.5%	13.9%
Ornstein, 1997 [10]	2	BPH	84	CVt	15%	16.5%
Morote, 1999 [17]	4–8	PCa, BPH	107	CVt	15%	32%
Boddy, 2004 [30]	4	BPH	58	CVb	9.5%	na
Kobayashi, 2005 [18]	12	PCa, BPH	126	CVt	16.1%	15.4%
This study	2	PCa, BPH	149	CVt	11.0%	13.0%
	0.02	PCa, BPH	149	CVt	4.0%	6.6%

BPH, benign prostatic hyperplasia; CVb, coefficient of biological variation; CVt, coefficient of total variation; PCa, prostate cancer; na, not available