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. Author manuscript; available in PMC: 2013 Feb 14.
Published in final edited form as: Genet Epidemiol. 2008 May;32(4):285–300. doi: 10.1002/gepi.20304

TABLE IV.

Eight two-locus epistatic models

Model f22 f21 f20 f12 f11 f10 f02 f01 f00 p1 p2
Ep1 0.222 0.222 0.08 0.222 0.222 0.08 0.08 0.08 0.08 0.21 0.21
Ep2 0.26 0.08 0.08 0.08 0.08 0.08 0.08 0.08 0.08 0.577 0.577
Ep3 0.24 0.24 0.08 0.24 0.08 0.08 0.08 0.08 0.08 0.349 0.349
Ep4 0.267 0.267 0.18 0.267 0.267 0.18 0.18 0.18 0.08 0.053 0.053
P1 0.08 0.07 0.05 0.1 0 0.1 0.08 0.1 0.04 0.25 0.25
P2 0 0 0.1 0 0.05 0 0.1 0 0 0.5 0.5
P3 0.07 0.05 0.02 0.05 0.09 0.01 0.02 0.01 0.08 0.1 0.1
P4 0.09 0.001 0.02 0.08 0.07 0.005 0.003 0.007 0.02 0.1 0.1

fij is the penetrance of a genotype carrying i high-risk alleles at locus 1 and j high-risk alleles at locus 2. p1 and p2 are the allele frequencies of high-risk alleles at locus 1 and locus 2, respectively.