Table S2.

Comparison of experimental and in silico result in case of ppc knockout mutant

Reaction	Trend of reaction as per literature	Trend of reaction as per in silico system
Pyruvate to acetyl coenzyme A	Increases	Increases
Malate to oxaloacetate	Increases	Increases
Oxaloacetate to phosphoenol pyruvate***	Decreases	Decreases
Malate to pyruvate	Increases	Increases

Note:

^***Data taken from Fong et al.29