Table 1.
General data in the 5/6 nephrectomized (CRF) and control (CTL) rats
| CTL | CRF | |
|---|---|---|
| Body weight 12 wk (g) | 459.80 ± 21.51 | 411.74 ± 55.36 |
| Liver weight 12 wk (g) | 15.18 ± 1.80 | 16.10 ± 1.44 |
| Heart left ventricle weight 12 wk (g) | 1.27 ± 0.08 | 1.50 ± 0.10** |
| Systolic blood pressure 12 wk (mmHg) | 123.52 ± 13.37 | 168.80 ± 2.83** |
| Diastolic blood pressure 12 wk (mmHg) | 87.50 ± 10.09 | 117.00 ± 4.53* |
| 24-h urine protein 12 wk (mg/day) | 6.70 ± 1.27 | 80.28 ± 7.31** |
| Hematocrit (%) | 48.91 ± 4.43 | 38.12 ± 9.64* |
| Plasma glucose (mg/dL) | 162.47 ± 23.82 | 168.04 ± 37.88 |
| Plasma urea nitrogen (mg/dL) | 25.37 ± 2.06 | 60.04 ± 16.42*** |
| Plasma creatinine (mg/dL) | 0.50 ± 0.14 | 2.22 ± 1.51* |
| Creatinine clearance (mL/min/m2) | 5.62 ± 1.18 | 1.45 ± 0.72*** |
N= 6 in each group. Data are means ± SD.
*P < 0.05 versus control group.
**P < 0.01 versus control group.
***P < 0.001 versus control group.