Table 3.

Risk of cognitive impairment^† on the Modified Mini Mental State Exam by tertile of pulse wave velocity after 9 years of follow-up, Health Aging and Body Composition study

	Model 1*	Model 2*	Model 3*
	OR (95% CI)	OR (95% CI)	OR (95% CI)
PWV tertile
Low (ref)	1	1	1
Middle	1.50 (1.13; 1.99)	1.34 (0.99; 1.79)	1.40 (1.03; 1.92)
High	1.63 (1.22; 2.19)	1.48 (1.09; 2.00)	1.59 (1.16; 2.18)

PWV indicates pulse wave velocity

^*Model 1 was unadjusted; Model 2 adjusted for age, sex, race, and education; Model 3 was additionally adjusted for APOE4, body mass index, high density lipoprotein, diabetes, hypertension, and mean arterial blood pressure

^†Cognitive impairment is defined as a decline of 5 or more points