Table 1.

Pathways involving BEAF-32-bound genes up-regulated by transcription changes in cells lacking BEAF-32 in wing imaginal tissue. The classification and analysis is based on gene id and nature of response seen in mutant tissue. The p value (in parenthesis) is calculated based on significant representation of genes with respect to the total number of genes involved in the pathway using the Ingenuity Pathway Analysis program (IPA).

Name of the upregulated pathway	Pathway component, gene name
Glutathione metabolism (2.86E00)	Zw, Gclc, Tina-1
CDK5 Signaling (2.6E00)	CG6191, mys, Mbs, SNF4Agamma
DNA double-strand break repair by non-homologous end joining (2.48E00)	Irbp, Lig4
IGF-1 signaling (2.43E00)	Pxn, S6k, InR, SNF4Agamma
PTEN signaling (1.5E00)	mys, S6k, InR
Insulin receptor signaling (1.98E00)	S6k, Ptp61F, Mbs, SNF4Agamma
FAK signaling (1.73E00)	mys, Pxn, CalpA
ILK signaling (1.53E00) HIF1α signaling (1.55E00) Integrin signaling (1.44E00) ERK/MAPK Signaling (1.52E00)	mys, Pxn, Mmp1, SNF4Agamma, Flo, sima, Hph
NRF2-mediated oxidative stress response (1.58E00)	MRP, CG5001, MRP
Caveolar-mediated endocytosis signaling (1.92E00)	mys, Ptp61F, Flo
Amyloid processing (1.33E00)	SNF4Agamma, CalpA
Actin cytoskeleton signaling (1.33E00)	mys, Pxn, DIAPH2, Mbs
Cell polarity genes	Baz
JNK signaling	Upd3, Socs35