Table 2.
Cause of community-acquired pneumonia in hospitalized children and role of viruses in six recent studies
| Juven et al,68 2000 (N = 254) |
Michelow et al,69 2004 (N = 154) |
Cevey-Macherel et al,66 2009 (N = 99) |
Tsolia et al,70 2004 (N = 75) |
Garcia-Garcia78 (N = 884) |
Jain et al,67 2011 (N = 1320a) |
|
|---|---|---|---|---|---|---|
| Age | 1 mo–17 y | 2 mo–17 y | 2 mo–5 y | 5–14 y | <14 y | 1 mo–17 y |
| Any pathogen | 85% | 79% | 86% | 77% | Not stated | 82% |
| Any bacteria | 53% | 60% | 52% | 40% | 2.2% | 10% |
| Any virus | 62% | 45% | 66% | 65% | 73%b | 77% |
| Coinfection | 30% | 23% | 33% | 28% | 22% | 23% |
| RSV | 29% | 13% | 13% | 3% | 31% | 25% |
| Influenza virus | 4% | 22% | 14% | 7% | 5% | 4% |
| hMPV | NS | NS | 13% | 1% | 5% | 1% |
| Adenovirus | 7% | 7% | 7% | 12% | 13% | 1% |
| Parainfluenza virus | 10% | 13% | 13% | 8% | 5% | 1% |
| Rhinovirus/enterovirusc | 24% | 4% | 33% | 45% | 19% | 31% |
| Coronavirus | 3% | NS | 7% | NS | 1% | <1% |
Abbreviation: NS, not sought.
a
Preliminary results from an ongoing study.
b
Includes detection of bocavirus in 13%.
c
Most assays identify both rhinovirus and enterovirus.