Wnt signaling determines the polarity of VPC cell divisions. (A) In the presence of posterior-expressed Wnt ligand egl-20 and AC-expressed Wnt ligands lin-44 and mom-2, P5.p and P7.p have mirror-image symmetry in their cell division patterns, which is termed “refined polarity” 61. (B) When lin-44 and mom-2 are absent, egl-20 directs a posterior-oriented “ground polarity”, such that both P5.p and P7.p divide in the same orientation. (C) In the absence of lin-44, mom-2, and egl-20, P5.p and P7.p divide with random polarity. This is considered the “default polarity” 61.