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. Author manuscript; available in PMC: 2013 Feb 14.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Jul 29;412(2):341–346. doi: 10.1016/j.bbrc.2011.07.100

Fig. 1.

Fig. 1

EGF receptor rapidly translocates to the nucleus in liver cells. (A) Immunoblots of total and phosphorylated EGF receptor (pEGFR) in non nuclear and nuclear fractions of SKHep-1 cells stimulated with EGF (100 ng/mL) are shown. α-tubulin and Lamin B1 were used as purity controls for the non nuclear and nuclear fractions, respectively. Total as well as phosphorylated EGFR are detected in the nucleus within 5 min of stimulation. (B) Immunoblots of total EGF receptor in non nuclear and nuclear fractions of hepatocytes stimulated with EGF (100 ng/mL). Blots are representative of what was observed in three separate experiments.