Table 2.

Association between CGG repeat length and intranuclear inclusion number on young and old female CGG KI mice.

	48–52 Weeks of Age		24–28 Weeks of Age
	Pearson’s rho	Slope	Pearson’s rho	Slope	Difference
Prelimbic cortex	ρ = 0.87; R2 = 0.77, p<0.01	0.194	ρ = 0.97; R2 = 0.95, p<0.01	0.07	0.12, p<0.05
Motor cortex	ρ = 0.91; R2 = 0.82, p<0.01	0.09	ρ = 0.91; R2 = 0.82, p<0.05	0.06	0.03, ns
Posterior parietal cortex	ρ = 0.80; R2 = 0.64, p<0.01	0.07	ρ = 0.97; R2 = 0.94, p<0.01	0.09	0.02, ns
Visual cortex	ρ = 0.92; R2 = 0.85, p<0.05	0.07	ρ = 0.96; R2 = 0.93, p<0.05	0.06	0.01, ns
Anterior cingulate cortex	ρ = 0.98; R2 = 0.97, p<0.01	0.17	ρ = 0.97; R2 = 0.95, p<0.05	0.14	0.03, ns
Piriform cortex	r = 0.99; R2 = 0.98, p<0.01	0.14	ρ = 0.98; R2 = 0.97, p<0.01	0.26	0.12, p<0.01
Entorhinal cortex
Ventromedial area	ρ = 0.95; R2 = 0.91, p<0.05	0.16	r = 0.96; R2 = 0.93, p<0.01	0.11	0.05, ns
Dorsolateral area	ρ = 0.93; R2 = 0.86, p<0.01	0.07	ρ = 0.96; R2 = 0.93, p<0.01	0.08	0.01, ns
Hippocampus
CA1	ρ = 0.96; R2 = 0.92, p<0.01	0.16	ρ = 0.89; R2 = 0.80, p<0.01	0.12	0.04, ns
CA3	ρ = 0.91; R2 = 0.83, p<0.05	0.09	ρ = 0.14; R2 = 0.02, p = 0.17	0.001	0.09, p<0.01
DG	ρ = 0.91; R2 = 0.84, p<0.01	0.50	ρ = 0.99; R2 = 0.99, p<0.001	0.43	0.07, ns
Subiculum	ρ = 0.94; R2 = 0.88, p<0.05	0.20	ρ = 0.90; R2 = 0.81, p<0.01	0.06	0.14, p<0.01
Amygdalar nuclei
Central nucleus	ρ = 0.88; R2 = 0.79, p<0.01	0.09	ρ = 0.98; R2 = 0.97, p<0.001	0.11	0.02, ns
Basolateral nucleus	ρ = 0.75; R2 = 0.55, p<0.01	0.15	ρ = 0.91; R2 = 0.83, p<0.001	0.11	0.04, ns
Posterior nucleus	ρ = 0.99; R2 = 0.79, p = 0.055	0.57	ρ = 0.98; R2 = 0.97, p<0.05	0.48	0.09, ns
Septal nuclei
Lateral septum	ρ = 0.82; R2 = 0.67, p = 0.061	0.02	ρ = 0.90; R2 = 0.81, p<0.05	0.04	0.02, ns
Medial septum	ρ = 0.67; R2 = 0.45, p<0.05	0.02	ρ = −0.77; R2 = 0.60, p<0.05	0.02	0, ns
LGN	ρ = 0.99; R2 = 0.99, p<0.001	0.31	ρ = 0.96; R2 = 0.9,2 p<0.01	0.17	0.14, p<0.01
Inferior colliculus	ρ = 0.90; R2 = 0.82, p<0.01	0.38	ρ = 0.99; R2 = 0.99, p<0.05	0.16	0.22, p<0.01
Superior colliculus	ρ = 0.95; R2 = 0.90, p<0.05	0.14	ρ = 0.94; R2 = 0.89, p = 0.053	0.02	0.12, p<0.05
Medial vestibular nucleus	ρ = 0.96; R2 = 0.93, p<0.01	0.14	ρ = 0.99; R2 = 0.98, p<0.01	0.13	0.01, ns
Cerebellum
Cerebellar lobule III
PCL	N/A	N/A	N/A	N/A
GCL	ρ = 0.97; R2 = 0.94, p<0.01	0.10	ρ = 0.83; R2 = 0.70, p<0.05	0.008	0.09, p<0.05
Flocculus
PCL	N/A	N/A	N/A	N/A
GCL	ρ = 0.95; R2 = 0.90, p<0.01	0.12	ρ = 0.94; R2 = 0.89, p<0.01	0.10	0.12, ns

Pearson’s correlation coefficients were calculated comparing CGG repeat length with intranuclear inclusion number. The differences in slopes of the correlation between young and old mice were compared. All p values have been FDR adjusted to control for false discovery rate (cf., Diep et al., 2012; Hunsaker et al., 2011c).