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. Author manuscript; available in PMC: 2013 Feb 14.
Published in final edited form as: Am J Transplant. 2008 Oct 31;9(1):74–82. doi: 10.1111/j.1600-6143.2008.02463.x

Figure 5. Nox-2 was associated with fibrogenesis in rat kidney allografts.

Figure 5

Immunoblot (A) and densitometry analyses (B) of kidney lysates from syngeneic transplants at 6 months were compared to kidney allografts 3 weeks and 6 months posttransplant. Data represented in (B) were normalized to GAPDH internal control and represent averages of three independent experiments. Allografts showed a significant increase in Nox-2 associated with greater α-SMA, nitrotyrosine and phosphorylated Smad2 levels whereas total Smad2 did not change significantly.