Table 4.

Statistical comparison of the corrected Cp ratio of the target-to-reference gene (formula 1) among the LPC, HPC and AD groups

(A) Corrected Cp ratio in the cerebellum
	IL-1β	IL-1ra	IL-6	IL-10	IL-13	IL-16	IL-18	IL-32	IL-33	IL-8	MCP-1	MIF	ICE	TACE	TGFβ1	TNFα
Kruskal-Wallis
(LPC-HPC-AD)	0.606	0.414	0.093	0.145	0.804	0.747	0.316	0.415	0.152	0.922	0.656	0.342	0.408	0.087	0.842	0.005
Steel-Dwass
LPC-HPC	0.962	1.000	0.121	0.857	0.857	0.981	0.493	0.540	0.251	0.924	0.997	0.924	0.636	0.142	0.924	0.285
HPC-AD	0.612	0.636	0.972	0.142	0.997	0.635	0.322	0.448	0.191	0.997	0.448	0.322	0.362	0.165	0.997	0.191
LPC-AD	0.753	0.362	0.177	0.362	0.818	0.962	0.972	0.962	0.988	0.951	0.972	0.588	0.993	0.775	0.818	0.003

(B) Corrected Cp ratio in the tem poral cortex
	IL-1β	IL-1ra	IL-6	IL-10	IL-13	IL-16	IL-18	IL-32	IL-33	IL-8	MCP-1	MIF	ICE	TACE	TGFβ1	TNFα
Kruskal-Wallis
(LPC-HPC-AD)	0.121	0.394	0.431	0.073	0.194	0.204	0.004	0.272	0.171	0.440	0.176	0.474	0.197	0.015	0.026	0.179
Steel-Dwass
LPC-HPC	0.781	0.997	0.540	0.997	0.818	0.997	0.893	0.972	0.857	0.818	0.997	0.540	0.588	0.988	0.818	0.403
HPC-AD	0.265	0.445	0.817	0.073	0.220	0.362	0.020	0.493	0.404	0.951	0.404	0.775	0.636	0.060	0.121	0.924
LPC-AD	0.140	0.493	0.540	0.191	0.341	0.205	0.009	0.251	0.165	0.322	0.142	0.683	0.191	0.018	0.027	0.165

Values: p, calculated by the Kruskal-Wallis and Steel-Dwass tests. Bold numbers: p<0.05.

The corrected Cp ratios of target (cytokine) to reference (PPIA) (formula 1) each in the cerebellum (A) and temporal cortex (B) were compared among the LPC, HPC and AD patient groups (Kruskal-Wallis test), and between the LPC and HPC, HPC and AD, and LPC and AD patient groups (Steel-Dwass test).