Table 2. Characteristics of the women who participated in the study according to infection status†.
No Malaria | P. vivax | P. falciparum | ||
Demographics | ||||
Age, years (mean (SD) [n]) | 23 (6) [41] | 24 (6) [59] | 23 (6) [19] | |
Gestational age, weeks (median (IQ) [n]) | 39 (38–40) [40] | 39 (38–40) [59] | 39 (38–40) [19] | |
Gravidity, (median (IQ) [n]) | 2 (1–4) [40] | 2 (1–4) [58] | 3 (1–6) [19] | |
Primigravidae, % | 44 | 31 | 26 | |
Clinical outcomes | ||||
Maternal Hb, g/dL (mean, SD) [n]) | 11.37 (1.40) [33] | 11.28 (1.77) [45] | 10.35 (1.46) [15] | |
Maternal hematocrit, % (mean (SD) [n]) | 34.17 (4.20) [41] | 34.13 (5.10) [59] | 31.26 (4.09) [19]◊ • | |
Maternal anemia, % | 36 | 42 | 53 | |
Birth weight, g (mean (SD) [n]) | 3192.20 (504.40) [41] | 3107.29 (564.12) [59] | 3131.67 (507.39) [18] | |
Low birth weight, % | 10 | 12 | 6 | |
Malaria history | ||||
Had previous infection in life, % [n] | 61 [41]§ | 100 [59] | 100 [19] | |
Ep. in current pregnancy, (median (min-max) [n]) | N/A | 1 (1–5) [59] | 1 (1–3) [19] | |
2+ infections during pregnancy (n/total) | N/A | 20/59 | 6/19 | |
Peripheral parasitemia at term, (n/total) | N/A | 3/59 | 4/19 | |
Month of infection, (mean (SD), [n]) | N/A | 5 (3) [58] | 6 (3) [17] | |
Trimester of infection, (% 1st/2nd/3rd) | N/A | 34/33/33 | 36/10/54 |
Women were grouped according to their malaria diagnoses during pregnancy, based on microscopy data. (SD) standard deviation. (IQ) 25th and 75th percentile. (n) number of women with data recorded. (%) percentage of total women in each group. (Hb) hemoglobin. (Ep.) number of episodes. (N/A) not applicable. Anemia: Hb<11 g/dL. Low birth weight: birth weight<2,500 g. 2+ infections during pregnancy: women with two or more infections detected over the duration of the pregnancy. Month of infection: Gestation month of first diagnosed infection. Trimester of infection: percentage of infections that were detected per trimester of gestation.
Student's t-test: P. falciparum vs. no malaria, P = 0.015.
Student's t-test: P. falciparum vs. P. vivax, P = 0.029.
χ2 test: no malaria vs. P. vivax or P. falciparum, P<<0.001.