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. 2013 Feb 14;8(2):e56015. doi: 10.1371/journal.pone.0056015

Figure 2. IgE induces collagen type-I deposition by ASMC through Igε-RI and Erk1/2 MAPK.

Figure 2

(A) Induction of collagen type-I deposition by IgE by ASMC and (B) the mediator role of Igε-RI and Igε-RII. (C) Contribution of MAPK to Igε-RI and Igε-RII signalling on IgE induced collagen type-I deposition by ASMC. (D) Specificity of IgE neutralising antibody treatment on combined TGF-β1 and IgE collagen type-I deposition by ASMC.