Table 2. Cross-reactive neutralizing antibody titers against 11 EV71 genotypes in children infected by EV71 C2, C4, B4 and B5 genotypes.
Year of collection (genotype) | ID | Age | A-70 | B1-86 | B2-86 | B3-97 | B4-02 | B5-08 | C1-98 | C2-98 | C3-00 | C4-05 | C4-08 | C5-07 |
1998(C2) | 1 | 1.7 | 64 | 256 | 512 | 256 | 256 | 256 | 256 | 256 | 256 | 512 | 1024 | 256 |
2 | 4.1 | 32 | 64 | 128 | 64 | 32 | 64 | 64 | 32 | 32 | 64 | 128 | 64 | |
3 | 3.1 | 64 | 256 | 256 | 256 | 512 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | |
4 | 0.8 | 64 | 512 | 512 | 256 | 256 | 256 | 1024 | 256 | 256 | 256 | 512 | 512 | |
1998(C2) | 5 | 1.5 | 2048 | 8192 | 8192 | 4096 | 4096 | 4096 | 16384 | 8192 | 4096 | 8192 | 8192 | 4096 |
6 | 0.8 | 256 | 1024 | 1024 | 1024 | 512 | 512 | 2048 | 1024 | 1024 | 1024 | 256 | 1024 | |
7 | 0.6 | 128 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 256 | 128 | 256 | 256 | |
8 | 0.8 | 128 | 1024 | 512 | 1024 | 512 | 512 | 256 | 256 | 512 | 512 | 1024 | 512 | |
9 | 3.8 | 128 | 2048 | 256 | 2048 | 512 | 1024 | 1024 | 1024 | 1024 | 1024 | 1024 | 1024 | |
10 | 4.2 | 128 | 512 | 512 | 512 | 512 | 256 | 512 | 256 | 256 | 512 | 512 | 512 | |
2005(C4) | 11 | 1.1 | 256 | 512 | 1024 | 1024 | 1024 | 1024 | 512 | 256 | 512 | 1024 | 2048 | 512 |
12 | 4.3 | 128 | 512 | 512 | 128 | 256 | 256 | 256 | 256 | 256 | 256 | 512 | 256 | |
2010(C4) | 13 | 4.4 | 128 | 256 | 512 | 512 | 512 | 512 | 128 | 1024 | 256 | 512 | 512 | 512 |
14 | 1.4 | 1024 | 2048 | 2048 | 4096 | 4096 | 2048 | 2048 | 4096 | 2048 | 2048 | 8192 | 2048 | |
15 | 2.4 | 32 | 128 | 128 | 64 | 128 | 128 | 128 | 256 | 64 | 128 | 256 | 128 | |
2000(B4) | 16 | 2.8 | 64 | 256 | 512 | 512 | 128 | 256 | 256 | 128 | 128 | 256 | 512 | 128 |
17 | 0.5 | 64 | 256 | 512 | 512 | 512 | 256 | 256 | 256 | 128 | 256 | 128 | 256 | |
18 | 3.1 | 32 | 128 | 512 | 256 | 256 | 256 | 128 | 128 | 128 | 128 | 64 | 128 | |
19 | 2.7 | 16 | 64 | 64 | 64 | 32 | 64 | 64 | 16 | 32 | 32 | 32 | 32 | |
20 | 1.3 | 32 | 128 | 128 | 128 | 512 | 128 | 64 | 64 | 256 | 64 | 64 | 64 | |
2008(B5) | 21 | 2.08 | 32 | 64 | 512 | 128 | 64 | 128 | 32 | 32 | 128 | 32 | 64 | 64 |
22 | 2.00 | 64 | 128 | 256 | 256 | 64 | 256 | 32 | 128 | 128 | 64 | 32 | 128 | |
23 | 2.25 | 64 | 128 | 512 | 256 | 128 | 256 | 64 | 128 | 256 | 64 | 128 | 128 | |
24 | 2.08 | 64 | 128 | 512 | 256 | 64 | 128 | 128 | 128 | 256 | 64 | 64 | 128 | |
25 | 2.25 | 32 | 64 | 128 | 128 | 128 | 128 | 64 | 128 | 128 | 64 | 64 | 64 |