Table II.

Associations between patient demographics, histology parameters and mortality.

Variable	No. of patients	1-year mortality (%)	2-year mortality (%)	Hazard ratio	95% confidence interval	P-value
Gender
Male	89	39 (43.8%)	51 (57.3%)	1	Ref.
Female	61	23 (37.7%)	39 (54.1%)	0.75	0.50–1.13
Age (years)
≤50	27	7 (26%)	15 (55.6%)	1	Ref.	0.17
51–70	71	25 (35.2%)	36 (50.7%)	0.99	0.57–1.71	0.98
≥71	52	30 (57.7%)	33 (63.5%)	1.45	0.83–2.54	0.19
Stage
I–III	82	16 (19.5%)	26 (31.7%)	1	Ref.	>0.0001
IV	68	46 (67.6%)	58 (85.5%)	4.14	2.76–6.21
Histology
Well diff.	10	3 (30%)	3 (30%)	1	Ref.	0.43
Moderate diff.	31	10 (32.3%)	15 (48.4%)	1.14	0.46–2.84	0.77
Signet ring and poorly diff.	97	46 (47.4%)	61 (63%)	1.47	0.64–3.40	0.36
Mucinous	12	3 (25%)	5 (41.7%	0.90	0.30–2.68	0.85
HER2 status
Negative	136	53 (39%)	74 (54.4%)	1	Ref.	0.10
Positive	14	9 (64%)	10 (71.4%)	1.68	0.90–3.15
Cyclin D1
≤5%	15	7 (46.7%)	10 (66.7%)	1	Ref.	0.88
6–49%	72	28 (39%)	38 (52.8%)	0.89	0.45–1.76	0.73
≥50%	63	27 (43%)	36 (57%)	0.97	0.49–1.93	0.94

Diff., differentiated.