Table IV.

Association between the expression of indicators of phosphorylation and those of proliferation, growth, apoptosis, angiogenesis, invasion and metastasis.

	P-value
Indicator expression	AKT	pAKT	ERK	pERK
Proliferation and growth
Ki-67	0.125	0.001	0.020	0.013
Cyclin D1	0.889	0.349	0.596	0.098
EGFR	0.296	0.029	0.370	0.002
Apoptosis
Bcl-2	0.051	<0.001	0.003	<0.001
Bax	0.031	0.451	0.012	0.081
Angiogenesis
VEGF	0.086	0.003	0.048	0.102
MVD	0.079	0.841	0.560	0.073
Invasion and metastasis
MMP-9	0.427	0.161	0.275	0.003
MMP-2	0.572	0.041	0.086	0.010
TIMP-2	0.167	0.456	0.587	0.084
E-cadherin	0.014	0.202	0.110	0.391