Table VII.
Uni- and multivariate analyses of clinicopathological variables and the expression of CXCR1/2 with regard to N stage.
Univariate analysis
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Multivariate analysis
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Variables | OR | 95% CI | P-value | OR | 95% CI | P-value |
CXCR1/2 (negative, weak vs. strong) | 23.571 | 7.121–77.945 | <0.001 | 29.108 | 5.807–146.057 | <0.001 |
pERK (negative, weak vs. strong) | 5.155 | 1.910–13.902 | 0.001 | 5.523 | 1.283–23.807 | 0.022 |
EGFR (negative, weak vs. strong) | 2.983 | 1.012–8.802 | 0.047 | 7.243 | 1.022–51.367 | 0.048 |
VEGF (negative, weak vs. strong) | 0.610 | 0.257–1.449 | 0.262 | 0.106 | 0.022–0.514 | 0.005 |
MVD (<20 vs. ≥20) | 5.686 | 2.201–14.673 | <0.001 | 6.398 | 1.779–23.035 | 0.004 |
CXCR1/2, C-X-C chemokine receptor types 1/2; OR, odds ratio; 95% CI, 95% confidence interval; MVD, microvessel density.