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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Free Radic Biol Med. 2012 Oct 5;62:157–169. doi: 10.1016/j.freeradbiomed.2012.09.027

Table II.

List of different functions of enolase and their possible implications in disease.

Enolase functional diversity Disease
GLYCOLYSIS/GLUCONEOGENESIS Various human diseases(cancer, neurological disease, autoimmunity, etc);
C-MYC BINDING PROTEIN Tumar formation/Tumor marker;
PLASMINOGEN BINDING PROTEIN Various human diseases(cancer, neurological disease, autoimmunity, etc);
HEAT-SHOCK PROTEIN Saccharomyces cervesiae
IMMUNODOMINENT ANTIGEN Candida infection
NEUROTROPHIC FACTOR Activation of pro-survival ERK1/2

- = unknown function