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. 2013 Feb;34(2):446–450. doi: 10.3174/ajnr.A3219

Table 2:

MRI findings observed in 8 patients after proton therapy

Time from Completion of Proton Therapy to First MRI with Changes (mo) Time from Appearance of Changes to Start of Resolution of Changes (mo) Location of Abnormal Signal/Enhancement Physical Examination Findings
Patient
    1 5.3 2.2 Brain stem, cerebellum, upper cervical spinal cord None
    2 3.6 2.3 Brain stem Unilateral weakness
    3 5.6 3 Cerebellum None
    4 3.4 3.1 Right thalamus (no enhancement) Unilateral weakness
    5 6.3 2.2 Brain stem None
    6 4.2 1.5 Brain stem and cerebellum Unilateral weakness
    7 3 Patient died of disease before follow-up Brain stem None
    8 3.2 3.5 Brain stem Ataxia
Median 3.9 2.3 (of 7 with follow-up MRI)
Mean 4.3 2.5 (of 7 with follow-up MRI)